Accel-Amplicon® Plus Colorectal (CRC) Cancer Panel

Simultaneous detection of genes implicated in colorectal cancer.

The Accel-Amplicon Plus Colorectal Cancer Panel is an NGS multigene panel for variant discovery and screening. It combines content from peer reviewed publications and other sources to offer comprehensive and exon-level hotspot coverage of 16 clinically-relevant colorectal genes. Areas of interest include genes such as AKT1, TP53, PIK3CA, KRAS and NRAS.

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The panel is modular, allowing you to add focused content to achieve your most optimal design. Either combine pre-validated content such as our Lynch Syndrome content or add your own targets.  We’ll work alongside you to design your assay and then Swift will optimize and wet-bench validate its performance before shipping it to you.

Comprehensive: Covers 11,000 COSMIC and 3,500 ClinVar mutations and generates targeted libraries compatible with Illumina® sequencing platforms.

Informative:  Provides CNV detection of ERBB2 and full exon coverage of TP53 with flanking intron/exon boundaries.

Powerful:  Simultaneous detection of single nucleotide variants (SNV), copy number variants (CNV) and small insertions and deletions (indels), all within a fast and easy single-tube assay workflow.

Flexible:  Add our Lynch Syndrome pre-validated content or your own targets using our pre-validated primers or other content. The possibilities are endless.

Other key features include: 

  • Robust performance on cell-free DNA and FFPE samples starting with as little as 10 ng input.
  • Highly sensitive detection of rare variants down to 1% allele frequency.
  • Easy, single-tube assay with sequence ready libraries in under 2 hours.
  • Streamlined analysis with bioinformatics tools including Primerclip.
  • Compatible with all Illumina sequencers

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DATA SHEET
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PANEL-SPECIFIC BIOINFORMATICS FILES
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WORKFLOW
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PANEL SPECIFICATIONS
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PERFORMANCE DATA
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AVAILABLE DATA ANALYSIS
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PROTOCOLS, TOOLS & TECHNICAL NOTES
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