Accel-Amplicon® Plus Lynch Syndrome Panel

Simultaneous detection of genes implicated in Lynch Syndrome.

varsome

The Accel-Amplicon Plus Lynch Syndrome Panel is the NGS multigene panel to identify mutations in DNA Mismatch Repair (MMR) genes.  It offers comprehensive and exon-level hotspot coverage of 4 clinically-relevant genes: MLH1, MSH2, MSH6 and PMS2. And with sensitivity down to 1% allele frequency, now you can identify both germline and somatic mutations in the same panel.

Comprehensive: Covers 600 COSMIC and 7,500 ClinVar mutations and generates targeted libraries compatible with Illumina® sequencing platforms.

Powerful:  Simultaneous detection of single nucleotide variants (SNV) and small insertion and deletions (indels), all within a fast and easy single-tube assay workflow.

Other key features include: 

  • Robust performance on cell-free DNA and FFPE samples starting with as little as 10 ng input.
  • Highly sensitive detection of rare variants down to 1% allele frequency.
  • Easy, single-tube assay with sequence ready libraries in 2 hours.
  • Streamlined analysis with new bioinformatics tools including Primerclip or VarSome.
  • Compatible with all Illumina sequencers

Frequently Asked Questions →