Accel-NGS® Methyl-Seq DNA Library Kit

For the Preparation of Bisulfite Converted Libraries

Accel NGS Methyl Seq product photo

The Accel-NGS Methyl-Seq DNA Library Kit maximizes DNA recovery of bisulfite-converted samples and resultant libraries accurately represent sample base composition on Illumina® NGS Platforms. The kit currently provides the most comprehensive coverage of the methylome and is an excellent choice for bisulfite sequencing applications, as well as targeted sequencing, such as RRBS and hybridization capture using the NimbleGen™ SeqCap™ Epi Enrichment System. The Accel-NGS Methyl-Seq Kit is also compatible with bisulfite-converted DNA samples enriched by ChIP or other methods as well as ancient DNA samples that may contain uracil nucleotides as a result of damage.

Features:

  • High recovery of input DNA
  • Low bias library preparation
  • Simple, 2-hour protocol
  • Inputs from 100 pg to 100 ng
  • Minimal PCR cycles required

Benefits:

  • Maintain precious samples
  • Reveals the complete methylome
  • Processing more samples/day
  • Use multiple sample types
  • Reduced amplification errors

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“We have been using Swift’s Accel NGS Methyl-Seq DNA Library kit since 2017. It is our go-to kit to determine the methylation status of circulating cell-free DNA at the genome level. The Swift Methyl-Seq kit has consistently produced high-quality libraries for our technically challenging whole genome bisulfite sequencing. We are confident in the complexity and yield, with steady reliable performance that exceeds our stringent quality metrics for our lab and our global collaborators. I highly recommend this kit to anyone performing methylation sequencing. It is a great assay and more people should know about it!”
-Renowned Philadelphia Institution

For Customers Outside the United States: Please request a quote or select from our list of distributors.

DATA SHEET
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APPLICATION NOTE
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WORKFLOW
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PERFORMANCE DATA – WGBS
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PERFORMANCE DATA – TARGETED
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PROTOCOLS, TOOLS & TECHNICAL NOTES
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