Genotyping

Genotyping can span the range from whole genome sequencing (WGS) of large genomes to small panels targeting single nucleotide polymorphisms (SNPs).   As the cost of next-generation sequencing (NGS) decreases and bioinformatics analysis improves, the utility and accessibility of WGS continues to expand.  However, as WGS sample throughput increases, preparing high-quality libraries from a wide range of sample inputs and types in a timely manner is a bottleneck impeding sequencing productivity.

Whether you are new to NGS or your capabilities already include high throughput automated WGS, the Swift library kits can help maximize your data output, giving you the best genome wide coverage of any kit on the market and reducing your sequencing costs.  Our Accel-NGS 2S DNA Library kit represents the leading kit in the field for low input, or damaged samples. Swift 2S Turbo brings a fast workflow and enzymatic shearing to the Swift WGS library kits.  Both these kits are excellent for genotyping both human and other samples. When combined with Normalase Kits, a streamlined workflow can be achieved for mid to high throughput workflows.

If your workflow requires targeted sequencing, Swift has both hybridization capture and amplicon panels to fit your needs.  Swift Hybridization Capture Kits enable enrichment and sequencing of the human exome or subsets of disease-related genes involved in cancer and inherited diseases. Our kits save sequencing costs by targeting only genes of interest using a 4-hour capture, while delivering the breadth and depth of coverage required for comprehensive yet sensitive genomic profiling.

The Accel-Amplicon Sample ID panel can be used to confidently track and manage samples during human genotyping studies.  With 95 primer pairs targeting exonic single SNPs with high minor allele frequency (MAF) and 9 amplicons to determine gender, Sample ID brings a discrimination power of 1:85000, which can be useful in a variety of fields including NIPT, and longitudinal studies and forensics.  Swift Accel-Amplicon kits are also available for targeted sequencing of the BRCA1 and BRCA2, TP53, and CFTR genes and for genes related to Lynch Syndrome. Swift is also adept at making high throughput custom genotyping panels for agricultural and metagenomic applications and infectious disease.

genotyping

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WGS

For inputs < 1ng

Exome and Hybridization Capture Sequencing

Suitable for cfDNA and FFPE

Targeted Amplicon Sequencing

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