Single-Cell Methylation Profiling of Pediatric Tumors via a Unique NGS-based Approach

This webinar will illustrate how single-cell methylation sequencing can be applied to gain significant insight into epigenetic heterogeneity in disease states, advancing cancer research discoveries.

Our speaker, Jennifer Flournoy of Perelman School of Medicine at the University of Pennsylvania, discusses a single-cell methylation approach from Swift Bioscience that her team is using to study pediatric leukemia and gliomas.

Jennifer FlournoyJennifer Flournoy
Research Specialist
Perelman School of Medicine at the University of Pennsylvania

Jen Flournoy is a Research Specialist in Hao Wu’s Lab at the University of Pennsylvania. She received her B.S. in Applied Mathematics and Statistics and a B.A. in Biology from Johns Hopkins University. She is working on single-cell DNA methylome analysis in pediatric tumors.

Hao Wu, PhDHao Wu, PhD
Assistant Professor, Department of Genetics
University of Pennsylvania

Hao Wu is an Assistant Professor in the Department of Genetics, as well as a core member of the Epigenetics Institute at the University of Pennsylvania. He received his BS in Biological Sciences from Tsinghua University before moving to the University of California Los Angeles, where he earned a PhD in Molecular Pharmacology for work in Yi Eve Sun’s laboratory studying epigenetic regulation of neural stem cell differentiation in mouse brains and from human pluripotent stem cells. For his postdoctoral training, he joined the laboratories of Yi Zhang and Kenneth Chien at Harvard University, where he developed and applied new genomics sequencing methods for investigating roles of novel DNA modifications and epigenetic gene regulatory mechanisms in mammalian pluripotent stem cells and during heart development.