New targeted sequencing workflow combines pre-validated content with easy customization and new analysis tools to accelerate variant discovery and screening

(ANN ARBOR, Mich. – April 18, 2018) Swift Biosciences today announced the commercial release of its Accel-Amplicon™ Plus Cancer Panels, a suite of nine tumor-specific and focused gene panels to facilitate targeted cancer sequencing. The Accel-Amplicon technology enables simultaneous detection of single nucleotide variants, copy number variants and small insertion and deletions to achieve comprehensive and exon-level hotspot coverage of clinically-relevant genes. It also allows researchers to combine pre-validated content and their own targets into a fast, single-tube assay to develop more informative and scalable workflows to better achieve their scientific goals.

 Every tumor harbors a unique combination of genomic alterations, which may determine tumor growth rate and response to treatment. Targeted sequencing using focused, multigene panels provides a precise and informative method to quickly identify clinically actionable variants within known or putative cancer genes. However, developing cancer gene panels requires bioinformatics expertise to identify genetic markers and additional resources to design, optimize and validate an assay.

Accel-Amplicon Plus provides a modular, mix-and-match capability that gives translational laboratories greater flexibility to deploy more than one strategy. Laboratories may either begin with a broad gene set to comprehensively profile tumors and then refine the content to the most informative markers, or start with a very focused assay to routinely screen known, clinically actionable variants. Each assay can be designed to accommodate up to 1500 amplicons per panel, are designed and wet-lab validated by Swift’s experts, and are fully compatible with degraded FFPE or diluted liquid biopsy samples.

“Accel-Amplicon Plus Cancer Panels could revolutionize cancer and oncology research,” said Haley Fiske, Chief Commercial Office at Swift Biosciences. “By integrating pre-validated and customizable content into a single panel, clinical researchers can maximize data generated from every tumor sample and accelerate their efforts to discover and screen cancer variants.”

The Accel-Amplicon Plus Cancer Panels consist of nine assays:

Disease Panels

  • Accel-Amplicon™ Plus Colorect